Table 5. Hazard Rate Ratios (HRR) with: (i) 1:1 matching for being diagnosed with any type of cancer following stemmed MoM in men (a: n = 17,450; 1,879 were subsequently diagnosed with cancer) and women (c: n = 16,930; 1,437 were subsequently diagnosed with cancer), and MoM hip resurfacings in men (b: n = 23,722; 1,529 were subsequently diagnosed with cancer) and women (d: n = 10,672; 704 were subsequently diagnosed with cancer).
Bearing type for first primary hip | (i) 1:1 matching | (ii) 1:4 matching | ||||
---|---|---|---|---|---|---|
Total number of cases (number who developed cancer) | HRR [95% CI] | p-value | Total number of cases (number who developed cancer) | HRR [95% CI] | p-value | |
Men | ||||||
(a) | 17,450 (1,879) | 41,000 (4,462) | ||||
Other | 1 [referent] | 1 [referent] | ||||
MoM | 0.98 [0.89–1.07] | p = 0.592 | 1.00 [0.93–1.07] | p = 0.966 | ||
(b) | 23,722 (1,529) | 38,350 (2,684) | ||||
Other | 1 [referent] | 1 [referent] | ||||
Resurfacing | 0.88 [0.80–0.97] | p = 0.013 | 0.84 [0.76–0.92] | p<0.001 | ||
Women | ||||||
(c) | 16,930 (1,437) | 41,815 (3,704) | ||||
Other | 1 [referent] | 1 [referent] | ||||
MoM | 0.98 [0.88–1.09] | p = 0.702 | 0.92 [0.85–1.00]] | p = 0.060 | ||
(d) | 10,672 (704) | 20,425 (1,375) | ||||
Other | 1 [referent] | 1 [referent] | ||||
Resurfacing | 0.95 [0.83–1.10] | p = 0.521 | 0.97 [0.85–1.11] | p = 0.697 |