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. 2018 Sep 20;13(9):e0204356. doi: 10.1371/journal.pone.0204356

Table 5. Hazard Rate Ratios (HRR) with: (i) 1:1 matching for being diagnosed with any type of cancer following stemmed MoM in men (a: n = 17,450; 1,879 were subsequently diagnosed with cancer) and women (c: n = 16,930; 1,437 were subsequently diagnosed with cancer), and MoM hip resurfacings in men (b: n = 23,722; 1,529 were subsequently diagnosed with cancer) and women (d: n = 10,672; 704 were subsequently diagnosed with cancer).

(ii) 1:4 matching for being diagnosed with any type of cancer following stemmed MoM in men (a: n = 41,000; 4,462 were subsequently diagnosed with cancer) and women (c: n = 41,815; 3,704 were subsequently diagnosed with cancer), and MoM hip resurfacings in men (b: n = 38,350; 2,684 were subsequently diagnosed with cancer) and women (d: n = 20,425; 1,375 were subsequently diagnosed with cancer).

Bearing type for first primary hip (i) 1:1 matching (ii) 1:4 matching
Total number of cases (number who developed cancer) HRR [95% CI] p-value Total number of cases (number who developed cancer) HRR [95% CI] p-value
Men
(a) 17,450 (1,879) 41,000 (4,462)
Other 1 [referent] 1 [referent]
MoM 0.98 [0.89–1.07] p = 0.592 1.00 [0.93–1.07] p = 0.966
(b) 23,722 (1,529) 38,350 (2,684)
Other 1 [referent] 1 [referent]
Resurfacing 0.88 [0.80–0.97] p = 0.013 0.84 [0.76–0.92] p<0.001
Women
(c) 16,930 (1,437) 41,815 (3,704)
Other 1 [referent] 1 [referent]
MoM 0.98 [0.88–1.09] p = 0.702 0.92 [0.85–1.00]] p = 0.060
(d) 10,672 (704) 20,425 (1,375)
Other 1 [referent] 1 [referent]
Resurfacing 0.95 [0.83–1.10] p = 0.521 0.97 [0.85–1.11] p = 0.697