Table 8. Cox proportional hazards regression models of the risk of being diagnosed with malignant melanoma following primary hip replacement by bearing type for men (n = 163,111; 576 were subsequently diagnosed with malignant melanoma) and women (n = 240,765; 596 were subsequently diagnosed with malignant melanoma).

Bearing type for first primary hip	(i) Unadjusted		(ii) Adjusted for age and ASA		(iii) Adjusted for age, ASA and whether patient had a record in PEDW
	HRR [95% CI]	p-value	HRR [95% CI]	p-value	HRR [95% CI]	p-value
Men
Other	1 [referent]		1 [referent]		1 [referent]
MoM	0.87 [0.64–1.18]	p = 0.359	1.13 [0.83–1.54]	p = 0.441	1.13 [0.83–1.54]	p = 0.451
Resurfacing	0.38 [0.26–0.54]	p<0.001	0.75 [0.51–1.12]	p = 0.158	0.75 [0.51–1.11]	p = 0.156
Women
Other	1 [referent]		1 [referent]		1 [referent]
MoM	0.81 [0.55–1.19]	p = 0.287	0.92 [0.62–1.36]	p = 0.669	0.92 [0.62–1.36]	p = 0.672
Resurfacing	0.65 [0.39–1.06]	p = 0.085	0.95 [0.56–1.62]	p = 0.855	0.95 [0.56–1.62]	p = 0.854