Table 10. Cox proportional hazards regression models of the risk of being diagnosed with prostate cancer following primary hip replacement by bearing type for men (n = 163,111; 4,061 were subsequently diagnosed with prostate cancer).

Bearing type for first primary hip	(i) Unadjusted		(ii) Adjusted for age and ASA		(iii) Adjusted for age, ASA and whether patient had a record in PEDW		(iv) Adjust for ASA and whether patient records in PEDW (instrumental variable) and stratified by age
	HRR [95% CI]	p-value	HRR [95% CI]	p-value	HRR [95% CI]	p-value	HRR [95% CI]	p-value
Other	1 [referent]		1 [referent]		1 [referent]		1 [referent]
MoM	0.65 [0.57–0.74]	p<0.001	0.91 [0.80–1.04]	p = 0.179	0.91 [0.80–1.04]	p = 0.164	0.90 [0.79–1.03]	p = 0.126
Resurfacing	0.45 [0.39–0.51]	p<0.001	1.16 [1.01–1.33]	p = 0.037	1.16 [1.01–1.33]	P = 0.040	1.11 [0.97–1.28]	p = 0.141