Table 1.
Influence of solvent on yield in final product a
Experiment. | Solvent | Temperature (°C) | Yield (%) b |
---|---|---|---|
1 | DMSO | 160-170 | 35 |
2 | DMF | 140-150 | 27 |
3 | HMPTA | 160-170 | 21 |
4 | NMP | 180-190 | 80 |
a) Experiments were performed on the reaction system corresponding to cinnamic acid 3a (see Scheme 1)
b) After recrystallization