Table 2.
Demographics of patients with ABPA and known fungal loads determined by Aspergillus-specific qPCR
| Total | rs35699176−/− (n = 36) | rs35699176+/− (n = 9) | P-value | |
|---|---|---|---|---|
| BMI (kg/cm2) | 26.59 ± 3.69 | 26.58 ± 3.52 | 26.75 ± 2.62 | ns |
| Smokers or ex-smokers (%) | 35% | 36% | 33% | ns |
| BTS score (median) | 4 | 4 | 4 | ns |
| Forced expiratory volume first second (FEV1, l) | 1.83 ± 0.79 | 1.83 ± 0.80 | 2.07 ± 0.75 | ns |
| Forced vital capacity (FVC, l) | 3.18 ± 1.02 | 3.2 ± 1.03 | 3.2 ± 0.98 | ns |
| FEV1/FVC (%) | 57 ± 13 | 56 ± 12 | 58 ± 14 | ns |
| Total IgE > 1000 IU (%) | 37.7% | 36.10% | 44.40% | ns |
| Aspergillus PCR (Ct) | 37.37 ± 5.08 | 37.57 ± 2.7 | 35.7 ± 1.1 | 0.01 |
| % Positive PCR | 71.1% | 63% | 100% | 0.04 |
Mean and standard deviation is shown
BTS British thoracic score, FVC forced vital capacity, FEV1 forced expiratory volume measured during the first forced breath