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. 2018 Sep 21;38(5):BSR20180790. doi: 10.1042/BSR20180790

Figure 3. LINC00473 promotes Taxol resistance via miR-15a in CRC cells.

Figure 3

(A) The IC50 of Taxl in HCT116/Taxol and HCT116 was determined by CCK-8. (B) The expressions of miR-15a and LINC00473 in HCT116/Taxol and HCT116 cells were determined by Q-PCR. (C) The HCT116/Taxol cells were transfected of siRNA of LINC00473 with or without miR-15a inhibitors, then the cells were treated with 0.5 μg/ml Taxol and the cell vitality was estimated by CCK-8. Besides, (D) the proliferation, (E) apoptosis and (F) the ability of migration and invasion were determined by colony formation assay, flow cytometry and transwell assay. *P<0.05, **P<0.01, ***P<0.001, data represent the means ± s.d.