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. 2018 Sep 21;38(5):BSR20180303. doi: 10.1042/BSR20180303

Figure 2. Smad1/5 is altered by BMP4 or BMSC-CM in NSCs.

Figure 2

The representative Western blot showed that the expression of Smad1/5 was up-regulated by BMP4 and blocked with the treatment of Noggin. In contrast, BMSC-CM alone could down-regulate the expression of Smad1/5, and it partly decreased the expression of Smad1/5 in the presence of BMP4. The data were expressed as mean ± SD (one-way ANOVA for Smad1 expression: F = 61.356, P<0.001, df1/df2 = 4/10, n=3; one-way ANOVA for Smad5 expression: F = 121.289, P<0.001, df1/df2 = 4/10, n=3; one-way ANOVA: *P<0.05; NS = P>0.05).