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. 2018 Sep 20;9(10):952. doi: 10.1038/s41419-018-0980-4

Fig. 5. RB1CC1 promotes pancreatic fibrosis in CP mice.

Fig. 5

a The H&E and Masson assays were conducted to indicate CP and pancreatic fibrosis in mice models of sham, CP (7 d, 14 d, and 21 d), sh-RB1CC1, and CP plus sh-RB1CC1 groups (n = 6) (bars = 50μm). b The expressions of α-SMA, Collagen I, Collagen III, LC3B, and RB1CC1 were analyzed in four different groups (n = 6) (bars = 50μm). c, d The qRT-PCR assays were performed to determine the expressions of RB1CC1 and α-SMA in mice pancreas in negative control, CP (21 d), CP plus sh-NC injection, and CP plus sh-RB1CC1 injection groups (n = 6). e The plasma RB1CC1 levels were compared in four different groups (n = 6). Data are expressed as mean ± SD. The results are representative of three independent experiments (*p < 0.05, **p < 0.01, and ***p  < 0.001)