Table 5.
Statistical analysis of the effect of TGF-β on hLFs OCR and ECAR
| TGF-β Effect (P Value) in IPF and Control (OCR)* |
TGF-β Effect (P Value) in IPF and Control (ECAR) |
|||||
|---|---|---|---|---|---|---|
| Time | IPF | Control | Difference* | IPF | Control | Difference* |
| All | 18.0 (<0.001) | 28.0 (<0.001) | −9.9 (0.12) | 52.4 (<0.001) | 120.4 (<0.001) | −68.0 (<0.001) |
| Basal | 20.0 (0.008) | 24.8 (0.004) | −4.8 (0.7) | 45.9 (<0.001) | 109.8 (<0.001) | −63.9 (0.002) |
| FCCP | 16.8 (0.14) | 41.5 (0.008) | −24.7 (0.2) | 56.8 (<0.001) | 120.5 (<0.001) | −63.7 (0.010) |
| Oligomycin | 19.2 (0.001) | 21.8 (0.001) | −2.6 (0.8) | 52.5 (<0.001) | 135.5 (<0.001) | −83.0 (0.001) |
| Rotenone | 16.4 (0.001) | 23.7 (<0.001) | −7.2 (0.3) | 54.5 (<0.001) | 115.9 (<0.001) | −61.3 (0.008) |
*
After-before TGF-β in IPF – after-before TGF-β in control.