Fig. 8. miR-665 promotes HCC metastasis in vivo.

a, b Bioluminescent images of mice administered with HepG2 (a) and SMMC-7721 (b) cells via the tail veins. Images were taken after 6 weeks. n = 5 per group. c Overall survival of each group mice injected with HepG2 cells. d Overall survival of each group of mice injected with SMMC7721 cells. e PTPRB and VEGF-A staining was analyzed in tumor tissues from each group of mice injected with HepG2 cells. f PTPRB and VEGF-A staining in tumor tissues from each group of mice injected with SMMC-7721 cells. All data are represented as means ± SD. ^* P < 0.05, ^** P < 0.01, ^*** P < 0.001