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. 2018 Sep 20;8:14145. doi: 10.1038/s41598-018-32459-2

Figure 4.

Figure 4

Distribution of extracellular matrix and cell nuclei along skeletal elements. Top: distribution of the area of extracellular matrix along the element. Middle: distribution of number of cells represented by the area of cell nuclei. Bottom: ratio between the area of cell nuclei and the area of extracellular matrix; the red-dotted line fits the data by a second order polynomial. The minimum of the parabola sits in the centre of the diaphyseal regions.