Table 6.
Multivariable analysis of factors associated with preference for performing total colectomy vs. segmental resection in Lynch Syndrome patients under age 50a
| Variables | Number of respondents who prefer total colectomy with ileorectal anastomosis or proctocolectomy in the case of rectal cancer (percentage within each category) | Odds ratio (95% Confidence Interval) |
|---|---|---|
| Gastroenterology (GI) subspecialty | ||
| General GI | 153 (57.3) | 1.00 |
| GI Oncology Specializations | 12 (80.0) | 1.35 (0.33, 5.45) |
| All other GI Specializations | 52 (61.9) | 0.95 (0.55, 1.65) |
| Urban/rural location | ||
| Urban | 189 (61.2) | 1.23 (0.68, 2.23) |
| Rural | 28 (49.1) | 1.00 |
| Practice setting | ||
| Academic Center | 74 (74.8) | 2.20 (1.20, 4.03) |
| Non-academic Center | 144 (53.9) | 1.00 |
| Career stage | ||
| Fellows in training | 33 (71.7) | 1.50 (0.70, 3.24) |
| In practice from 0 to 10 years | 77 (63.6) | 1.44 (0.89, 2.34) |
| In practice from 11+ years | 108 (54.0) | 1.00 |
| Familiarity with the guideline | ||
| Familiar | 109 (67.3) | 1.62 (0.92, 2.85) |
| Unsureb | 64 (51.6) | 0.90 (0.50, 1.61) |
| Unfamiliarc | 46 (55.4) | 1.00 |
a59.4% of total respondents surveyed prefer total colectomy or proctocolectomy for LS patients <50 years old, whereas 37.4% prefer the same operation in those age >50 years old (p<0.0001)
bUnsure means they are not clear on whether they are aware of the applicable guidelines or not
cUnfamiliar means providers are not well versed with current guidelines