Table 2. Clinical status in 33 cases of acute respiratory failures received bronchoalveolar lavage (BAL) using high-flow nasal cannula oxygen delivery.
No | Age (yr)/ Sex | PF ratio | Before BAL | After BAL | During BAL | Procedure time (min) | Intubation* (time to intubation, hr) | Immune Suppression | 6-Month survival | Complications | Pre-BAL diagnosis | Infectious agent | Post-BAL diagnosis | Treatment change | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FiO2 | Flow (L/min) | SpO2 (%) | FiO2 | Flow (L/min) | SpO2 (%) | FiO2 | Flow (L/min) | SpO2 (%) | ||||||||||||
1 | 80/F | 109.6 | 0.7 | 40 | 93 | 0.9 | 40 | 98 | 0.8 | 40 | 90 | 20 | + (26) | - | Expired | THX, fever | PN | Acinetobacter baumanii | PN | - |
2 | 56/M | 165.6 | 0.6 | 50 | 90 | 0.9 | 50 | 96 | 0.6 | 50 | 90 | 5 | + (76) | - | Expired | THX, fever | ILD | - | ILD | - |
3 | 43/F | 133.3 | 0.4 | 5 | 96 | 0.7 | 60 | 98 | 0.7 | 60 | 98 | 20 | - | - | Expired | Fever | PN | - | AH | + |
4† | 42/F | 165.3 | 0.4 | 5 | 97 | 0.9 | 50 | 96 | 0.4 | 5 | 95 | 30 | - | - | Expired | Fever | PN | PCP | APN | + |
5† | 42/F | 173.8 | 0.4 | 5 | 93 | 0.94 | 50 | 94 | 0.65 | 50 | 98 | 30 | - | - | Expired | THX, fever | APN | PCP | APN | - |
6 | 71/M | 159.3 | 0.4 | 5 | 98 | 0.5 | 50 | 98 | 0.5 | 50 | 96 | 20 | - | - | Survived | Fever | PN | - | PN | - |
7 | 83/M | 138.9 | 0.45 | 47 | 98 | 0.7 | 47 | 96 | 0.5 | 47 | 97 | 20 | - | - | Survived | - | PN | - | OP | + |
8 | 73/F | 115.8 | 0.5 | 50 | 90 | 0.9 | 50 | 95 | 0.6 | 50 | 98 | 15 | - | - | Survived | - | PN | - | OP | + |
9 | 56/M | 200.0 | 0.4 | 30 | 98 | 0.56 | 50 | 91 | 0.5 | 40 | 99 | 15 | - | - | Expired | THX | PN | Staphylococcusaureus | PN | + |
10 | 68/F | 212.3 | 0.4 | 5 | 96 | 0.6 | 50 | 97 | 0.4 | 5 | 96 | 15 | - | - | Survived | Hypotension | PN | A. baumanii,S. aureus | PN | + |
11 | 82/F | 213.9 | 0.4 | 5 | 99 | 0.6 | 45 | 99 | 0.4 | 5 | 96 | 9 | - | + | Survived | - | APN | - | APN | - |
12 | 53/M | 269.5 | 0.4 | 40 | 97 | 0.4 | 40 | 90 | 0.4 | 40 | 99 | 25 | + (32) | - | Expired | THX | APN | RSV | APN | + |
13 | 23/M | 203.8 | 0.3 | 3 | 96 | 1.0 | 55 | 86 | 0.6 | 40 | 94 | 7 | - | - | Survived | THX | APN | - | AEP | + |
14 | 70/M | 149.5 | 0.4 | 30 | 96 | 0.6 | 50 | 90 | 0.4 | 30 | 95 | 9 | - | - | Survived | - | PN | CMV | APN | + |
15 | 73/F | 106.3 | 0.6 | 50 | 94 | 0.8 | 55 | 92 | 0.7 | 50 | 93 | 10 | + (70) | - | Expired | THX, fever | APN | - | APN | - |
16 | 58/M | 178.2 | 0.6 | 50 | 91 | 1.0 | 50 | 88 | 0.8 | 50 | 91 | 21 | - | - | Survived | THX | PN | RSV | OP | + |
17 | 64/M | 120.8 | 0.4 | 40 | 96 | 0.8 | 50 | 90 | 0.4 | 40 | 96 | 7 | - | - | Survived | - | PN | - | PN | - |
18 | 69/M | 128.0 | 0.4 | 35 | 98 | 0.4 | 35 | 97 | 0.4 | 35 | 97 | 9 | - | - | Expired | - | PN | - | PN | - |
19 | 64/F | 248.0 | 0.4 | 40 | 100 | 0.8 | 40 | 97 | 0.4 | 40 | 98 | 7 | - | - | Survived | - | APN | - | APN | - |
20 | 76/F | 123.1 | 0.65 | 45 | 98 | 1.0 | 60 | 94 | 0.65 | 45 | 95 | 20 | + (78) | + | Expired | THX | APN | - | APN | - |
21 | 70/M | 244.6 | 0.28 | 2 | 92 | 0.6 | 40 | 95 | 0.8 | 15 | 96 | 8 | + (144) | - | Expired | THX, fever | ILD | Candida albicans | APN | + |
22 | 56/F | 189.4 | 0.32 | 3 | 91 | 0.6 | 40 | 96 | 0.6 | 40 | 98 | 25 | - | + | Expired | THX | APN | CMV | APN | + |
23 | 72/M | 159.4 | 0.4 | 5 | 92 | 0.7 | 40 | 95 | 0.6 | 50 | 98 | 17 | - | + | Expired | THX | APN | CMV | APN | + |
24 | 64/M | 184.7 | 0.32 | 3 | 90 | 0.7 | 50 | 96 | 0.4 | 40 | 92 | 17 | + (120) | - | Expired | THX, fever | APN | - | APN | - |
25 | 36/F | 136.8 | 0.7 | 50 | 95 | 1.0 | 50 | 88 | 0.8 | 50 | 90 | 5 | - | - | Survived | THX | PN | - | OP | + |
26 | 81/M | 128.8 | 0.5 | 40 | 94 | 0.9 | 60 | 94 | 0.5 | 40 | 93 | 5 | - | - | Survived | THX | PN | C. albicans | PN | - |
27 | 68/F | 156.0 | 0.5 | 40 | 96 | 0.7 | 50 | 94 | 0.6 | 50 | 93 | 10 | + (72) | + | Expired | THX | AH | - | AH | - |
28 | 43/M | 89.1 | 0.7 | 60 | 91 | 0.8 | 60 | 93 | 0.8 | 60 | 95 | 7 | + (274) | + | Expired | THX | APN | PCP, CMV, Rhinovirus | APN | + |
29 | 71/M | 208.9 | 0.28 | 2 | 91 | 0.5 | 40 | 98 | 0.5 | 40 | 97 | 15 | - | - | Expired | - | PN | - | PN | + |
30 | 81/F | 245.8 | 0.4 | 40 | 95 | 0.8 | 50 | 97 | 0.6 | 50 | 100 | 12 | - | + | Expired | - | PN | C. albicans | ILD | + |
31 | 80/F | 141.0 | 0.4 | 5 | 98 | 1.0 | 60 | 100 | 0.6 | 50 | 93 | 14 | - | + | Expired | - | APN | - | APN | - |
32 | 64/M | 102.6 | 0.5 | 40 | 95 | 0.8 | 60 | 95 | 0.7 | 50 | 92 | 8 | - | - | Survived | - | PN | S. aureus | PN | + |
33 | 75/M | 179.2 | 0.4 | 5 | 95 | 0.4 | 40 | 99 | 0.4 | 40 | 95 | 18 | - | - | Survived | - | PN | Pseudomonas aeruginosa | PN | + |
*Cases for endotracheal intubation were followed until 2 weeks after the BAL procedure. †One patient received bronchoscopy twice for BAL.
PF ratio: baseline PaO2/FiO2; FiO2: fraction of inspired oxygen; Flow: gas flow rate; SpO2: oxygen saturation recorded by pulse oximetry; F: female; THX: transient hypoxemia; PN: bacterial pneumonia; M: male; ILD: interstitial lung disease; AH: alveolar hemorrhage; PCP: Pneumocystis jiroveci pneumonia; APN: atypical pneumonia; OP: organizing pneumonia; RSV: respiratory syncytial virus; AEP: acute eosinophilic pneumonia; CMV: cytomegalovirus.