Table 5. Logistic regression analysis of clinicopathological parameters for the prediction of false-positive patients with lung cancer.
Variable | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
OR (95% CI) | p-value | OR (95% CI) | p-value | |
Age, yr | ||||
<65 | 1.00 | 0.005 | 1.00 | 0.022 |
≥65 | 2.49 (1.31–4.73) | 2.21 (1.12–4.36) | ||
Histology | ||||
Adenocarcinoma vs. squamous cell carcinoma, large cell carcinoma, small cell carcinoma, and others | 0.82 (0.45–1.48) | 0.501 | - | - |
Squamous cell carcinoma vs. adenocarcinoma, large cell carcinoma, small cell carcinoma, and others | 2.93 (1.57–5.47) | 0.001 | 2.84 (1.48–5.43) | 0.002 |
Large cell carcinoma vs. adenocarcinoma, squamous cell carcinoma, small cell carcinoma, and others | 0.81 (0.09–7.41) | 0.853 | - | - |
Small cell carcinoma vs. adenocarcinoma, squamous cell carcinoma, large cell carcinoma, and others | 0.21 (0.07–0.62) | 0.004 | 0.18 (0.06–0.55) | 0.003 |
Others vs. adenocarcinoma, squamous cell carcinoma, large cell carcinoma, small cell carcinoma | 1.65 (0.30–9.26) | 0.568 | - | - |
Anthracosis or anthracofibrosis | ||||
Absence | 1.00 | 0.310 | - | - |
Presence | 1.70 (0.61–4.76) | - | ||
Pneumoconiosis | ||||
Absence | 1.00 | 0.018 | 1.00 | 0.020 |
Presence | 5.85 (1.35–25.27) | 6.33 (1.34–29.96) | ||
Old and active tuberculosis | ||||
Absence | 1.00 | 0.598 | - | - |
Presence | 0.82 (0.39–1.72) | - | ||
ILD | ||||
Absence | 1.00 | 0.661 | - | - |
Presence | 1.25 (0.46–3.35) | - | ||
Pneumonia | - | |||
Absence | 1.00 | 0.929 | - | - |
Presence | 1.04 (0.42–2.58) | - |
OR: odds ratio; CI: confidence interval; ILD: interstitial lung disease.