Table 1.
Baseline Characteristics of the 380 Non-anticoagulated Hemodialysis Patients in August 2011.
| Variable | AF (n=55) | Non-AF (n=325) | p | |||
|---|---|---|---|---|---|---|
| Age, yrs | 71.9±10.1 | 63.7±12.8 | <0.01 | |||
| Male | 39 | (71%) | 227 | (70%) | 0.87 | |
| BMI, kg/m2 | 21.7±4.1 | 20.6±3.7 | 0.05 | |||
| Duration of hemodialysis, mo | 187±157 | 126±113 | <0.01 | |||
| History of: | ||||||
| Coronary artery disease | 12 | (22%) | 43 | (13%) | 0.09 | |
| Congestive heart failure | 15 | (27%) | 58 | (18%) | 0.10 | |
| PCI | 9 | (16%) | 22 | (6%) | 0.01 | |
| CABG | 1 | (2%) | 5 | (1%) | 0.87 | |
| Valve surgery | 0 | 0 | ||||
| Pacemaker/ICD | 5 | (9%) | 2 | (1%) | <0.01 | |
| Ischemic stroke | 12 | (22%) | 36 | (11%) | 0.02 | |
| Peripheral artery disease | 15 | (27%) | 54 | (17%) | 0.06 | |
| Hypertension | 34 | (62%) | 231 | (71%) | 0.16 | |
| Dyslipidemia | 9 | (16%) | 80 | (25%) | 0.18 | |
| Diabetes | 14 | (26%) | 88 | (27%) | 0.80 | |
| Hemorrhagic stroke | 6 | (11%) | 21 | (7%) | 0.23 | |
| Gastrointestinal bleeding | 10 | (18%) | 35 | (11%) | 0.23 | |
| Cause of ESRD: | ||||||
| Diabetes | 14 | (26%) | 82 | (25%) | ||
| Glomerulonephritis | 21 | (38%) | 150 | (46%) | ||
| Hypertension | 4 | (7%) | 27 | (8%) | 0.64 | |
| Echocardiographic findings: | ||||||
| LVEF, % | 61±12 | 65±9 | <0.01 | |||
| LA, mm | 39±10 | 38±6 | 0.25 | |||
| LVH | 26 | (48%) | 120 | (37%) | 0.12 | |
| Laboratory data (pre-dialysis): | ||||||
| Creatinine, mg/dL | 8.6±2.9 | 11.2±4.3 | <0.01 | |||
| Hematocrit, % | 30.8±4.1 | 30.8±3.7 | 0.98 | |||
| Antithrombotic therapy | ||||||
| Aspirin | 17 | (31%) | 60 | (19%) | 0.03 | |
| Thienopyridine | 9 | (16%) | 35 | (11%) | 0.23 | |
| CHADS2score | 2.2±1.7 | 1.7±1.3 | 0.01 | |||
| HAS-BLED score | 4.0±1.2 | 3.1±1.1 | <0.01 | |||
AF: atrial fibrillation, BMI: body mass index, CABG: coronary artery bypass grafting, ESRD: end stage renal disease, ICD: implantable cardioverter defibrillator, LVDd: left ventricular diastolic dimension, LVEF: left ventricular ejection fraction, LVH: left ventricular hypertrophy, PCI: percutaneous coronary intervention