TABLE 2.
IS and composite transposons associated with resistance genes in staphylococci and enterococci
| ISa | Tn | Determinant | Associated resistance(s) | Hostb |
|---|---|---|---|---|
| IS16 | Tn1547 | vanB1 | Vancomycin | E |
| IS256 | cfr | Phenicols/lincosamides/oxazolidinones/pleuromutilins/streptogramin A | S | |
| Tn1547 | vanB1 | Vancomycin | E | |
| Tn4001 | aacA-aphD | Gentamicin/kanamycin/tobramycin | S | |
| Tn5281 | aacA-aphD | Gentamicin/kanamycin/tobramycin | E | |
| Tn5384 | aacA-aphD | Gentamicin/kanamycin/tobramycin | E | |
| Tn5384 | erm(B) | MLS antibiotics | E | |
| IS257c | aadD | Kanamycin/neomycin/paromomycin/tobramycin | S | |
| aphA-3 | Kanamycin/neomycin | S | ||
| bcrAB | Bacitracin | S | ||
| ble | Bleomycin | S | ||
| dfrK | Trimethoprim | S | ||
| erm(C) | MLS antibiotics | S | ||
| fosB5 | Fosfomycin | S | ||
| fusB | Fusidic acid | S | ||
| ileS2 (mupA) | Mupirocin | S | ||
| qacC | Antiseptics/disinfectants | S | ||
| sat4 | Streptothricin | S | ||
| tet(K) | Tetracycline | S | ||
| tet(L) | Tetracycline | S | ||
| vat(A) | Streptogramin A | S | ||
| vga(A) | Streptogramin A/pleuromutilins/lincosamides | S | ||
| vgb(A) | Streptogramin B | S | ||
| Tn924 | aacA-aphD | Gentamicin/kanamycin/tobramycin | E | |
| Tn4003 | dfrA | Trimethoprim | S | |
| Tn6072 | aacA-aphD | Gentamicin/kanamycin/tobramycin | S | |
| Tn6072 | spc | Spectinomycin | S | |
| IS1182 | Tn5405 | aadE | Streptomycin | S, E |
| Tn5405 | aphA-3 | Kanamycin/neomycin | S, E | |
| Tn5405 | sat4 | Streptothricin | S, E | |
| IS1216 | cfr | Phenicols/lincosamides/oxazolidinones/pleuromutilins/streptogramin A | E | |
| str | Streptomycin | E | ||
| Tn5385 | aacA-aphD | Gentamicin/kanamycin/tobramycin | E | |
| Tn5385 | aadE | Streptomycin | E | |
| Tn5385 | blaZ | Penicillins | E | |
| Tn5385 | erm(B) | MLS antibiotics | E | |
| Tn5385 | tet(M) | Tetracycline/minocycline | E | |
| Tn5482 | vanA | Vancomycin | E | |
| Tn5506 | vanA | Vancomycin | E | |
| IS1272 | TnSha1 | fabI | Triclosan | S |
| TnSha2 | fabI | Triclosan | S | |
| IS21-558 | cfr | Phenicols/lincosamides/oxazolidinones/pleuromutilins/streptogramin A | S | |
| lsa(B) | Lincosamides | S | ||
| ISEnfa4 | cfr | Phenicols/lincosamides/oxazolidinones/pleuromutilins/streptogramin A | S, E | |
| ISSau10 | aadD | Kanamycin/neomycin/paromomycin/tobramycin | S | |
| dfrK | Trimethoprim | S | ||
| erm(C) | MLS antibiotics | |||
| erm(T) | MLS antibiotics | S | ||
| tet(L) | Tetracycline | S |