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. 2018 Sep 20;8:14087. doi: 10.1038/s41598-018-32568-y

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The antinociceptive effects of Dezocine evaluated by the hot plate test (A), abdominal constriction test (D) and formalin test (E). (B) The analgesic effects of Dezocine following different routes of administration. (C) Time courses for the effects of Dezocine in producing antinociception. After injected with various doses of Dezocine and the reference drug morphine, the antinociception was measured. ED₅₀ values are shown in Table 3. Data are presented as mean ± SEM from at least 10 mice.