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. 2018 Sep 20;8:14087. doi: 10.1038/s41598-018-32568-y

Table 3.

ED50 values of the antinociception produced by Dezocine and Morphine.

Compounds Antinociception ED50 (mg/kg)
Hot plate test Abdominal constriction test Formalin test Phase I Phase II
Dezocine 0.2 (0.1–0.2) 0.4 (0.2–1.0) 0.4 (0.2–0.9)
Morphine 6.9 (5.6–8.5)a 0.8 (0.5–1.2)a 5.1 (4.3–5.9)b 3.1 (2.8–3.3)b

The antinociceptive ED50 values were calculated from data obtained at 15 min after drug administration. In parentheses are 95% confidence limits.

a,bThe data of morphine associated with hot-plate test, abdominal constriction test and formalin test were cited from our previous data34,35.