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. 2017 Aug 2;313(5):F1149–F1160. doi: 10.1152/ajprenal.00240.2017

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Fig. 5. — Effects on the basal activity in the bladder strips with the inhibitors of Rho-associated kinase (ROCK) and PKC. Left: changes in tone. PBOO + T mice showed a significant decrease in tone with Y-27632 compared with that in control group. The change in PBOO + P mice was similar to PBOO + T mice but statistically insignificant. Neither amplitude nor frequency of spontaneous contractions showed a significant difference among groups and between without drug and Y-27632 or bisindolylmaleimide-I (BIM-1) within each group. Changes in amplitude (middle) and frequency (right) are depicted as the percentage to the value without drug (taken as 100%). Values are means ± SE. *P < 0.05 vs. control group.