Table 2.

Comparison of proportional collagen in the bladders from 3 groups

Collagen	Control	PBOO + P	PBOO + T
To DSM	15.1 ± 3.0	28.4 ± 3.6*	21.9 ± 4.4
To total	25.3 ± 2.4	41.5 ± 5.5*	27.8 ± 1.8†

Values represent means ± SE (%). Areas of detrusor smooth muscle (DSM) layer or a whole section (total area) were taken as 100%. PBOO caused a significant increase in collagen level, while 17-DMAG treatment suppressed the collagen deposition in the obstructed bladders.

^*P < 0.05, vs. control group;

^†P < 0.05, PBOO + P vs. PBOO + T groups.