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Immunohistochemistry staining for MIF-2/D-DT in WT and Mif−/− mice 48 h after I/R or sham operation (Sham = non I/R kidney (control); I/R = bilateral 30 min I/R). WT I/R kidneys show focal cortical interstitial MIF-2/D-DT expression but no expression in glomeruli. Mif−/−I/R mice show strong MIF-2/D-DT expression in glomeruli, parietal cells and in cortical interstitial cells.
