Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A: RNAseq analysis in kidney 48 h post-I/R injury showed near complete absence of secretory leukocyte proteinase (SLPI) mRNA in Mif−/− animals compared with WT controls. Treatment with MIF-2/D-DT restored the SLPI mRNA levels to 60% of WT control levels. **P < 0.01; ***P < 0.001; n = 6–8 animals per group. B and C: treatment of MPT cells with MIF-2/D-DT (100 ng/ml) significantly increased SLPI abundance at 12, 18, and 24 h posthypoxic injury. *P < 0.05, **P < 0.01; n = 3–4 experiments.
