Table 2.
Free oxidized fatty acid levels in HDL and LDL fractions from RA patients compared to healthy controls
| Rheumatoid arthritis (n = 10) | Healthy control (n = 8) | P value | |
|---|---|---|---|
| HDL 5-HETE | 14.4 ± 5.8 | 5.8 ± 2.6 | 0.0009 |
| HDL 12-HETE | 155.9 ± 338.6 | 33.3 ± 8.0 | 0.3986 |
| HDL 15-HETE | 3.8 ± 2.2 | 1.4 ± 0.5 | 0.0029 |
| HDL 9-HODE | 27.7 ± 14.8 | 9.5 ± 5.7 | 0.0039 |
| HDL 13-HODE | 38.2 ± 19.9 | 13.7 ± 6.1 | 0.0039 |
| LDL 5-HETE | 0.58 ± 0.28 | 0.22 ± 0.14 | 0.0038 |
| LDL 12-HETE | 7.6 ± 9.5 | 3.4 ± 3.1 | 0.230 |
| LDL 15-HETE | 0.47 ± 0.17 | 0.21 ± 0.14 | 0.003 |
| LDL 9-HODE | 5.3 ± 3.6 | 1.8 ± 1.4 | 0.005 |
| LDL 13-HODE | 6.8 ± 4.5 | 2.3 ± 1.6 | 0.005 |
All units are nanograms per milliliter plasma
HDL high density lipoprotein, LDL low density lipoprotein, HETE hydroxyeicosatetraenoic acid, HODE hydroxyoctadecadienoic acid