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. 2018 Sep 21;7(9):737–749. doi: 10.1002/open.201800136

Table 1.

Effect of compounds on the inhibition of TNF‐α released by LPS induction from J774A.1 cells.

Compound Structure TNF‐α inhibition
IC50 [μm]
6 graphic file with name OPEN-7-737-g014.jpg 29
7 graphic file with name OPEN-7-737-g015.jpg 50
8 graphic file with name OPEN-7-737-g016.jpg >90
9 graphic file with name OPEN-7-737-g017.jpg >90
10 graphic file with name OPEN-7-737-g018.jpg 13
11 graphic file with name OPEN-7-737-g019.jpg 33
12 graphic file with name OPEN-7-737-g020.jpg >90
13 graphic file with name OPEN-7-737-g021.jpg >90
14 graphic file with name OPEN-7-737-g022.jpg 37
15 graphic file with name OPEN-7-737-g023.jpg >90
16 graphic file with name OPEN-7-737-g024.jpg >90
17 graphic file with name OPEN-7-737-g025.jpg >90
18 graphic file with name OPEN-7-737-g026.jpg >90
19 graphic file with name OPEN-7-737-g027.jpg 40
20 graphic file with name OPEN-7-737-g028.jpg >90
21 graphic file with name OPEN-7-737-g029.jpg >90
22 graphic file with name OPEN-7-737-g030.jpg >90
23 graphic file with name OPEN-7-737-g031.jpg >90
24 graphic file with name OPEN-7-737-g032.jpg 32[a]
25 graphic file with name OPEN-7-737-g033.jpg 26[a]
26 graphic file with name OPEN-7-737-g034.jpg >90
27 graphic file with name OPEN-7-737-g035.jpg 29[a]

[a] Compound showed cytotoxicity at this concentration.