Table 1. Clinicopathological features and MYCN status in 275 NBs.
Features | Number | MYCN-amplified | MYCN-unamplified |
---|---|---|---|
Sex | |||
Male | 170 | 39 | 131 |
Female | 105 | 20 | 85 |
Age(months) | |||
<18 | 124 | 20 | 104 |
18–60 | 102 | 33 | 69 |
≥60 | 49 | 6 | 43 |
Grade of differentiation | |||
Undifferentiated | 89 | 37 | 52 |
Poorly differentiated | 163 | 22 | 141 |
Differentiating | 23 | 0 | 23 |
Histology | |||
Favorable | 183 | 9 | 174 |
Unfavorable | 92 | 50 | 42 |
INSS stage | |||
1 | 44 | 1 | 43 |
2 | 9 | 1 | 8 |
3 | 62 | 11 | 51 |
4 | 143 | 45 | 98 |
4S | 17 | 1 | 16 |
Risk group | |||
Low | 55 | 1 | 54 |
Intermediate | 54 | 0 | 54 |
High | 166 | 58 | 108 |
Primary site | |||
Adrenal gland | 221 | 54 | 167 |
Mediastinum | 40 | 2 | 38 |
Others | 14 | 3 | 11 |
Distant metastatic site | |||
Bone | 109 | 28 | 81 |
Bone marrow | 84 | 23 | 61 |
Lymph node | 35 | 8 | 27 |
Liver | 36 | 11 | 25 |
Skin | 21 | 6 | 15 |
Others | 49 | 19 | 30 |