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. 2006 Jun 12;11(6):383–392. doi: 10.3390/11060383

Table 2.

Effect of different organic solvents on the synthesis of 3e

Entry a Reaction time / h organic phase The amount of solvent / mL Yield b / %
1 1 CHCl3 10 25.5
2 1 C6H6 10 45.2
3 1 CH3COOEt 10 54.3
4 1 Toluene 10 83.0

a Reaction conditions: A mixture of quinazolin-4-one (1 mmol) (2e), 1-bromopropane (1.0 mmol), Bu4NBr (0.08 mmol), 35 % potassium hydroxide (84 mmol, 10mL) in toluene (10 mL) was stirred at 88-90°C for 1 h. b Yields of isolated products.