Table 3.
Characteristics of main genes
| Gene | Degree | Betweenness |
|---|---|---|
| Average value | 5.928 | 2064.408 |
| PIK3CG | 46 | 41488.54899 |
| PIK3R3 | 41 | 25199.73317 |
| APP | 35 | 32767.23403 |
| MAPK8 | 33 | 35071.18269 |
| PRKACB | 29 | 27367.34287 |
| PTK2 | 28 | 25355.409 |
| ITGB1 | 28 | 17088.50374 |
| SMURF1 | 27 | 7546.059618 |
| SMURF2 | 27 | 6748.334913 |
| BUB1 | 26 | 11066.28571 |
| GNG4 | 26 | 10653.80228 |
| H2AFV | 25 | 20305.78635 |
| WNT5A | 25 | 13709.55435 |
| VEGFA | 23 | 20760.79426 |
| KIF23 | 21 | 10253.88184 |
| RAD51 | 21 | 17892.93805 |
| KIF11 | 21 | 5135.989346 |
| CCNF | 20 | 5540.628454 |
| RAP1A | 19 | 7521.72323 |
| PPP2R1B | 19 | 14143.0877 |
| BRCA1 | 19 | 6029.273042 |
| NEDD4 | 19 | 3192.727805 |
| CLASP1 | 19 | 7496.485807 |
| SYK | 19 | 11386.15814 |
| GSK3B | 19 | 18438.62749 |
| DNM2 | 19 | 5911.698768 |
| ADCY2 | 18 | 7560.286406 |
| ATM | 18 | 9420.324388 |
| CDKN1A | 18 | 18240.66944 |
| RHOT1 | 18 | 16492.35297 |
| HIP1R | 17 | 3517.329081 |
| RAP1B | 17 | 5215.72323 |
| MCM4 | 17 | 5808.281935 |
| UBE4A | 17 | 2304 |
| PARK2 | 17 | 2366.125584 |
| CDH1 | 17 | 14376.3563 |
| UBE2I | 17 | 10854.31473 |
| SYNJ2 | 17 | 5273.61775 |
| IL10 | 16 | 11158.43666 |
| LRP2 | 16 | 3590.998058 |
| KIAA0319 | 15 | 3475.143506 |
| RACGAP1 | 15 | 5861.489126 |
| ACTR1A | 15 | 3744.522591 |
| PRDM10 | 15 | 14008.2127 |
| FASLG | 15 | 5210.263877 |
| BMP2 | 15 | 5337.049932 |
| LDLR | 15 | 2191.70904 |
| HDAC9 | 15 | 10403.97449 |
| GRM5 | 14 | 3250.915796 |
| CASP8 | 14 | 5874.766056 |
| ESR1 | 14 | 11585.62988 |
| NFATC2 | 14 | 4879.928683 |
| PBK | 14 | 4821.131434 |
| VAV2 | 14 | 8716.774939 |
| GRM1 | 14 | 3250.915796 |
| FGFR1OP | 13 | 6727.611655 |
| DTL | 13 | 2540.356126 |
| TGFBR1 | 13 | 4022.943631 |
| CAMK2D | 13 | 5055.739472 |
| CASP9 | 12 | 4919.739038 |
| P2RY6 | 12 | 2304 |
| YWHAZ | 11 | 4040.292887 |
| MAP3K7 | 11 | 6201.810194 |
| FLT1 | 11 | 6634.16899 |
| PPP1CB | 11 | 2005.113067 |
| NCOA3 | 11 | 7457.814126 |
| FGFR2 | 11 | 3030.464668 |
| ITGA2 | 10 | 3529.023629 |
| NOTCH2 | 10 | 10947.19567 |
| CENPN | 10 | 1873.156984 |
| FGFR1 | 10 | 8007.32537 |
| IRF4 | 10 | 5202.998605 |
| PTBP1 | 10 | 6730.910039 |
| MEF2C | 10 | 4165.497288 |
| ARHGEF7 | 9 | 3147.468396 |
| TIAM1 | 9 | 4058.542014 |
| ERBB4 | 9 | 4519.484052 |
| ARCN1 | 9 | 2088.364196 |
| CASP7 | 9 | 5818.243304 |
| PGR | 9 | 4778.496029 |
| SPTBN1 | 9 | 10172.1474 |
| DMD | 9 | 2456.15705 |
| FZD3 | 9 | 2260.879218 |
| MAPK9 | 9 | 2693.578423 |
| DYNC1LI2 | 9 | 2495.446083 |
| NR3C1 | 9 | 4868.398944 |
| DVL3 | 9 | 3925.165711 |
| HDAC8 | 9 | 2385.834093 |
| APC | 9 | 4483.983598 |
| TNRC6A | 8 | 2766.776691 |
| RPS6KA1 | 8 | 2691.499073 |
| TJP1 | 8 | 4534.026739 |
| ACVR1B | 8 | 1933.546424 |
| TGFB2 | 8 | 2116.806735 |
| SP100 | 8 | 2757.903141 |
| POLR1E | 7 | 6748.802196 |
| ETS1 | 7 | 4087.280316 |
| CSNK1A1 | 7 | 2157.303406 |
| PSEN1 | 7 | 3233.020264 |
| TAF1 | 7 | 4214.786588 |
| ERC1 | 7 | 3537.432599 |
| CCNE2 | 7 | 1750.370853 |
| REL | 7 | 2794.403409 |
| MAPT | 7 | 2044.275299 |
| LIMK1 | 7 | 1750.999958 |
| CSF2RA | 7 | 1782.306466 |
| E2F2 | 7 | 4585.295895 |