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. 2018 Oct 1;106(4):420–431. doi: 10.5195/jmla.2018.345

Table 3.

Use of the patient, intervention, comparison, outcome (PICO) model compared to another conceptualizing model as a literature search strategy tool

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Study (author, year) Study design Searchers Calculation of primary outcomes Databases searched Comparison model or unguided search Sensitivity (%) Precision (%)
Agoritsas et al., 2012 [21] Observational study (no randomization, time series, or other study design indicated) Two study authors trained in epidemiology and evidence-based medicine (EBM) extracted search terms, which all coauthors approved. It is unclear who performed the searches. Sensitivity and precision calculations based on the relevance of the first 40 records in the search output as compared to a gold standard. PubMed PICO* Median: Median:
17.9§, ‡‡ 6.3§, ‡‡
26.1†, ‡‡ 8.8†, ‡‡
29.6†, ** 11.3†, **
15.5†, †† 20.0†, ††
54.7‡, ‡‡ 32.1‡, ‡‡
54.7‡, ** 32.8‡, **
15.5‡, †† 50.0‡, ††
PIC (truncated version of PICO)* Median: Median:
9.8§, ‡‡ 2.5§, ‡‡
14.6†, ‡‡ 5.0†, ‡‡
17.6†, ** 5.0†, **
48.5‡, ‡‡ 21.3 ‡, ‡‡
52.8‡, ** 23.8‡, **
PubMed link to related articles* Median: Median:
39.7§, ‡‡ 10.0§, ‡‡
37.9§, ‡‡ 10.0§, ‡‡
37.5§, ‡‡ 7.5§, ‡‡
Hoogendam et al., 2012 [22] Randomized controlled crossover trial 8 specialists and 14 residents with interest in vascular medicine. Sensitivity and precision calculations based on the relevance of all search output as compared to a gold standard. PubMed PICO Average: 13.62 Average:3.44
Unguided search Average: 12.27 Average:4.02
Methley et al., 2014 [23] Observational study (study design not indicated) Search strategy developed as collaboration between some or all study authors and a specialist librarian and information specialist. Sensitivity and precision calculations based on the relevance of all search output as assessed by the study authors. CINAHL PICO 77.78 1.04
Embase 72.22 0.1
MEDLINE 66.67 0.15
CINAHL PICOS 66.67 8.22
Embase 38.88 3.7
MEDLINE 33.33 5.32
CINAHL SPIDER 66.67 8.22
Embase 16.67 5.45
MEDLINE 27.78 35.71

* Queries were combined with a †broad therapeutic intervention filter, ‡a narrow therapeutic intervention filter, or §no filter and further limited to **English language and human studies; ††English language, human studies, and Abridged Index Medicus titles; or ‡‡no limitations.