TABLE VI.
Allele Distribution and Analysis of Common SNPs Grouped by Ethnicity*
| T-261G(n=147) | A-161T(n = 200) | C129T and G861T (n= 148)a | ||||
|---|---|---|---|---|---|---|
| T | G | A | T | C/G | T | |
| Caucasian American | 68 (56.7%) | 52 (43.3%) | 115 (71.0%) | 47 (29.0%) | 79 (64.8%) | 43 (35.2%) |
| African American | 100 (78.1%) | 28 (21.9%) | 174 (93.5%) | 12 (6.5%) | 105 (82.0%) | 23 (18.0%) |
| Hispanic American | 30 (65.2%) | 16 (34.82%) | 37 (71.1%) | 15 (28.9%) | 31 (67.4%) | 15 (32.6%) |
| Chi-square=13.08; | P=0.0014 | Chi-square=33.47; | P<0.0001 | Chi-square=10.13; | P=0.0063 | |
*
Individuals of mixed ethnicity are not included in analysis.
a
The C129T and G861C SNPs have been previously reported to be in complete linkage disequilibrium [Huang et al., 1999]. This finding was also observed in the study group reported here.