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Colloidal/nanosphere lithography on drop-cast chitosan thin films. (A) A drop-cast chitosan thin film; note the layers of chitosan nanoscale fibers; (B) 300 nm nanosphere mask on chitosan thin film—note the distortion of the polystyrene nanospheres as they are stretched across the surface of the chitosan substrate; (C) Post-reactive ion etch of a nanosphere-masked chitosan substrate—note the high-aspect ratio nanocone arrays; (D) Flexible nanostructured chitosan thin film.
