Table 3.
Major criteria | 1 | Hemoglobin > 16.5 g/dL in males and > 16.0 g/dL in females or Hematocrit > 49% in males and > 48% in females or Increased red cell mass |
2 | Bone marrow showing hypercellularity for age with panmyelosis and presence of proliferation of mature megakaryocytes | |
3 | Positive testing for JAK2 V617F or JAK2 exon 12 mutation | |
Minor criterion | Subnormal serum erythropoietin level |