Table 1.

Meta-analysis association test results for top SNPs, by histology type

Strata	SNP	Chr	Position	Nearest Gene	Function	Allelea	EAF	OR (95% CI)	P-value	Mean of QC Info Score
Overall	rs8040868	15q25.1	78911181	CHRNA3	Synonymous (V-V)	T_C	0.42	1.33 (1.23, 1.43)	4.38 × 10−13	0.99
SQC	rs71603396	4p15.31	18012035	LCORL	Intron	G_A	0.14	1.92 (1.55, 2.37)	1.73 × 10−9	0.88
	rs12686364	9p21.3	21670087	CDKN2A	Intergenic	A_G	0.004	8.49 (4.13, 17.46)	6.21 × 10−9	0.96

OR, odds (log additive) ratio; 95% CI, 95% confidence interval; SQC, squamous cell carcinoma.

^aDenotes reference_effect(coded) allele; Genome positions relative to GRCh37; EAF, effective allele frequency.