Table 2.
Lipid profile at different treatment durations, between the control and Nigella sativa groups.
| Variables (Mean ± SD) | Treatment duration | Control | N sativa | P value |
|---|---|---|---|---|
|
| ||||
| TG (mg/dL) | Baseline | 180.82 (124.14) (57) | 170.87 (102.19) (57) | .64 |
| 3 months | 185.82 (111.09) (52) | 168.35 (92.38) (51) | .38 | |
| 6 months | 193.49 (110.28) (51) | 167.06 (108.72) (50) | .22 | |
| 9 months | 184.02 (115.19) (48) | 162.34 (85.02) (50) | .29 | |
| 12 months | 189.72 (114.99) (48) | 169.62 (102.60) (48) | .36 | |
|
| ||||
| TC (mg/dL) | Baseline | 195.63 (46.30) (57) | 194.19 (40.58) (57) | .86 |
| 3 months | 199.30 (45.84) (52) | 185.56 (40.94) (51) | .11 | |
| 6 months | 200.94 (43.31) (51) | 177.64 (41.24) (50) | .007 | |
| 9 months | 195.64 (34.54) (48) | 180.18 (42.99) (50) | .05 | |
| 12 months | 199.27 (39.29) (48) | 180.66 (41.91) (48) | .02 | |
|
| ||||
| LDL-C (mg/dL) | Baseline | 122.98 (33.12) (57) | 126.49 (33.91) (57) | .57 |
| 3 months | 127.98 (30.02) (52) | 114.23 (35.29) (51) | .03 | |
| 6 months | 128.62 (35.93) (51) | 107.14 (36.48) (50) | .004 | |
| 9 months | 120.58 (27.73) (48) | 115.34 (38.50) (50) | .44 | |
| 12 months | 120.72 (26.96) (48) | 114.25 (34.62) (48) | .30 | |
|
| ||||
| HDL-C (mg/dL) | Baseline | 42.45 (10.05) (57) | 42.54 (43.01 (57) | .96 |
| 3 months | 42.21 (9.83) (52) | 43.01 (10.36) (51) | .68 | |
| 6 months | 41.70 (8.41) (51) | 42.68 (10.66) (50) | .61 | |
| 9 months | 43.25 (11.13) (48) | 45.02 (10.67) (50) | .42 | |
| 12 months | 43.79 (9.81) (48) | 44.02 (10.45) (48) | .91 | |
|
| ||||
| TC/HDL-C | Baseline | 4.72 (1.21) (57) | 4.76 (1.31) (57) | .88 |
| 3 months | 4.88 (1.32) (52) | 4.53 (1.39) (51) | .19 | |
| 6 months | 4.95 (1.26) (51) | 4.38 (1.33) (50) | .02 | |
| 9 months | 4.70 (1.07) (48) | 4.16 (1.22) (50) | .02 | |
| 12 months | 4.75 (1.23) (48) | 4.27 (1.40) (48) | .07 | |
|
| ||||
| LDL-C/HDL-C | Baseline | 3.00 (0.94) (57) | 3.12 (1.07) (57) | .53 |
| 3 months | 3.16 (0.94) (52) | 2.80 (1.12) (51) | .07 | |
| 6 months | 3.19 (1.01) (51) | 2.66 (1.08) (50) | .01 | |
| 9 months | 2.92 (0.88) (48) | 2.70 (1.10) (50) | .28 | |
| 12 months | 2.89 (0.80) (48) | 2.77 (0.98) (48) | .51 | |
Values are mean and standard deviation. Number of patients at each visit is given in parenthesis. The numbers vary because of drop-outs (Figure 1). Missing values were replaced by linear interpolation in SPSS. Comparisons between control and NS groups were done by independent sample t test. Statistically significant differences are bolded. TG: Triglycerides; TC: Total cholesterol; LDL-C: Low density lipoprotein cholesterol; HDL-C: High density lipoprotein cholesterol