Table 3.
Comparison of body mass index, heart rate, systolic blood pressure, diastolic blood pressure and mean arterial pressure at different treatment durations, between the control and Nigella sativa groups.
| Variables (Mean ± SD) | Treatment duration | Control | N sativa | P value |
|---|---|---|---|---|
|
| ||||
| BMI (kg/m2) | Baseline | 31.83 (3.93) (57) | 30.47 (3.99) (57) | .071 |
| 3 months | 32.09 (3.76) (52) | 30.68 (3.83) (51) | .064 | |
| 6 months | 32.15 (3.88) (51) | 30.76 (3.74) (50) | .071 | |
| 9 months | 32.06 (4.11) (48) | 30.69 (3.66) (50) | .085 | |
| 12 months | 32.14 (4.12) (48) | 30.84 (3.51) (48) | .101 | |
|
| ||||
| HR (beats/minute) | Baseline | 87.40 (8.83) (57) | 85.80 (7.64) (57) | .305 |
| 3 months | 87.57 (7.73) (52) | 84.09 ( 6.13) (51) | .013 | |
| 6 months | 88.19 (7.65) (51) | 84.04 (7.31) (50) | .006 | |
| 9 months | 88.45 (9.17) (48) | 84.28 (6.86) (50) | .013 | |
| 12 months | 88.16 (7.76) (48) | 82.68 (7.16) (48) | .001 | |
|
| ||||
| SBP (mmHg) | Baseline | 133.77 (14.37) (57) | 139.03 (15.68) (57) | .053 |
| 3 months | 131.53 (14.70) (52) | 133.92 (18.82) (51) | .475 | |
| 6 months | 131.76 (13.25) (51) | 132.90 (20.07) (50) | .738 | |
| 9 months | 134.68 (14.34) (48) | 132.00 (16.22) (50) | .388 | |
| 12 months | 134.37 (15.32) (48) | 129.37 (17.43) (48) | .139 | |
|
| ||||
| DBP (mmHg) | Baseline | 78.59 (7.60) (57) | 80.17 (8.34) (57) | .293 |
| 3 months | 78.26 (5.41) (52) | 76.27 (8.47) (51) | .157 | |
| 6 months | 78.52 (7.02) (51) | 76.10 (8.70) (50) | .126 | |
| 9 months | 80.41 (7.13) (48) | 77.20 (6.71) (50) | .024 | |
| 12 months | 79.89 (7.88) (48) | 76.66 (7.80) (48) | .47 | |
|
| ||||
| MAP (mmHg) | Baseline | 96.92 (7.89) (57) | 99.75 (9.26) (57) | .083 |
| 3 months | 96.23 (7.59) (52) | 95.31 (10.31) (51) | .607 | |
| 6 months | 95.67 (7.91) (51) | 95.11 (10.54) (50) | .607 | |
| 9 months | 98.77 (8.37) (48) | 95.69 (8.73) (50) | .078 | |
| 12 months | 98.15 (9.43) (48) | 94.01 (9.78) (48) | .038 | |
Values are mean and standard deviation. Number of patients at each visit is given in parenthesis. Number of patients varies because of drop outs. Missing values replaced by linear interpolation in SPSS. Comparisons between control and NS groups were done by independent sample t test. Statistically significant differences are bolded. BMI: body mass index; HR: heart rate; SBP: systolic blood pressure; DBP: diastolic blood pressure; MAP: mean arterial pressure.