Table 1.
Baseline characteristics
|
Control
n = 30 |
Rehabilitation
n = 30 |
p- Value | ||
|---|---|---|---|---|
| Age (years) | 64 (8) | 64 (13) | 0.81 | |
| Gender (men) | 15 (50%) | 22 (73%) | 0.06 | |
| BMI (Kg/m2) | 26 (5) | 28 (4) | 0.21 | |
| Diagnosis | ||||
| IIP | 10 (33%) | 11 (37%) | 0.79 | |
| • IPF | 7 (23%) | 7 (23%) | 1.0 | |
| • NSIP | 3 (10%) | 3 (10%) | 1.0 | |
| • DIP | 0 | 1 (3%) | 0.50 | |
| KNOWN CAUSES | 12 (40%) | 16 (53%) | 0.30 | |
| • Chronic HP | 4 (13%) | 12 (40%) | 0.02 | |
| • Asbestosis | 0 | 1 (3%) | 0.50 | |
| • Drug induced ILD | 1 (3%) | 1 (3%) | 1.0 | |
| • CTD-ILD | 7 (23%) | 2 (7%) | 0.14 | |
| UNCLASSIFIABLE ILD | 8 (27%) | 3 (10%) | 0.09 | |
| Steroids | 14 (47%) | 15 (50%) | 0.80 | |
| SVC | (L) | 2.6 (1.1) | 2.9 (0.7) | 0.35 |
| (%pred) | 77 (22) | 76 (20) | 0.86 | |
| DLCO | (mmol.min−1.kPa− 1) | 3,4 (1,1) | 4 (1,6) | 0.11 |
| (%pred) | 41 (13) | 45 (16) | 0.30 | |
| PaO2 (mmHg) | 77 (14) | 76 (11) | 0.71 | |
| 6MWD | (m) | 491 (95) | 462 (123) | 0.32 |
| (%pred) | 79 (14) | 71 (16) | 0.045 | |
| Wmax (%pred) | 71 (26) | 61 (20) | 0.10 | |
| QF (%pred) | 81 (36) | 78 (23) | 0.70 | |
| HF (%pred) | 85 (27) | 89 (23) | 0.61 | |
| SGRQ total (points) | 40 (18) | 42 (14) | 0.68 | |
| Physical Activity (PA) | ||||
| • Steps per day | 7182 (3523) | 5745 (3312) | 0.12 | |
| • MPA | 57 (21–158) | 36 (10–130) | 0.14 | |
Data expressed as mean (SD) or numbers and MPA as geometric mean (geometric interval): geometric mean is antilog(m) and geometric interval is (antilog(m-SD) – antilog(m + SD)), m and SD being the mean and the standard deviation of the log-transformed MPA, respectively. BMI body mass index, IIP idiopathic interstitial pneumonia, IPF idiopathic pulmonary fibrosis, NSIP nonspecific interstitial pneumonia, DIP desquamative interstitial pneumonia, HP hypersensitivity pneumonitis, CTD-ILD connective tissue disease-related ILD, SVC slow vital capacity, DLco diffusion capacity for carbon monoxide, PaO2 partial pressure of oxygen at breathing room air, 6MWD six-minute walking distance, Wmax maximal workload, QF quadriceps force, SGRQ St George's respiratory questionnaire, MPA moderate intense physical activity (dailt time spent in activities with an intensity of at least 3 METs)a. p-values in bold indicate a statistically significant difference between intervention and control group