Table 1.
Characteristics of the five patients
| At diagnosis | |
|---|---|
| Age (median, ranges) | 72 (17 to 96) |
| Gender (M/F) | 1/4 |
| Comorbidities | |
| Hypertension | 2/5 |
| Tobacco | 2/5 |
| Diabetes mellitus | 0/5 |
| Toxic exposure | 0/5 |
| Pulmonary symptoms | 3/5 |
| Mechanical ventilation required | 1/5 |
| Serum creatinine μmol/L (median, ranges) | 605 (47 to 800) |
| Dialysis required at diagnosis | 4/5 |
| Proteinuria g/L (median, ranges) | 4 (0.2 to 6) |
| Biological characteristics | |
| Hemoglobin g/L (mean, ranges) | 95 (76 to 116) |
| Anti-GBM titer of dilution (IIF) (mean, ranges) | 97 (5 to 640) |
| ANCA + | 2/5 |
| Crescents > 50% on biopsy | 2/3 |
| Treatment | |
| Number of plasma-exchange sessions, mean (range) | 16 (9 to 23) |
| Corticosteroids | 5/5 |
| Rituximab as a first-line treatment | 5/5 |
Abbreviations: F female, M male, IIF indirect immunofluorescence, ANCA anti-neutrophil-cytoplasmic antibody, anti-GBM anti glomerular-basement-membrane