. 2007 Feb 5;12(2):139–148. doi: 10.3390/12020139

Table 1.

Antimicrobial effects of 1-alkanols on the growth of S. aureus and n-octanol/water partition coefficients.

Alcohol	Broth dilution method		Broth dilution with shaking			log₁₀P_o/w
Alcohol	MIC	MBC	MIC	MBC	DP*	log₁₀P_o/w
1-Octanol	256	256	N.D.	N.D.	0.0	3.07^a
1-Nonanol	64	128	N.D.	N.D.	17.5	4.02^a
1-Decanol	32	64	40	80	≥ 48.0	4.57^a
1-Undecanol	16	32	40	40	≥ 48.0	4.53^b
1-Dodecanol	8	16	10	N.D.	≥ 48.0	5.13^a
1-Tridecanol	4	8	10	N.D.	≥48.0	5.59^b
1-Tetradecanol	4	8	N.D.	N.D.	29.7	6.03^a
1-Pentadecanol	4	8	N.D.	N.D.	27.2	6.24^c
1-Hexadecanol	256	≥ 512	N.D.	N.D.	17.3	6.65^d
1-Heptadecanol	≥ 512	≥ 512	N.D.	N.D.	6.5	7.23^c
1-Octadecanol	≥ 512	≥ 512	N.D.	N.D.	10.0	7.19^d

N.D. = Not detected at the concentration tested.

* = Delay in proliferation was calculated from growth curves ([1-alkanol]= 40 μg mL^-1)

^a Japan Oil Chemists’ Society. The Handbook of Oil Chemistry 4^th ed.; Maruzen: Tokyo, 2001.

^b S. A. Chicu et al., Quant. Struct.-Activ. Relation. 2002, 19, 227-236.

^c Calculated value (W. M. Meylan et al. J. Pharm. Sci. 1995, 84, 83-92).

^d L. P. Burkhard et al. Chemosphere 1985, 14, 1551-1560.