Table 1. Levels of hippocampal BDNF, PSD95, SYP, IL-6, and FNDC5 of male 5×FAD^CTL, 5×FAD^ProAHN, 5×FAD^+AHN(RUN), and 5×FAD^ΨAHN(RUN) mice.

Animal numbers in parentheses (female mice in Table S7). F_(3,31) = 11.48, P < 0.01 (BDNF); F_(3,41) = 6.279, P < 0.01 (PSD95); F_(3,41) = 6.083, P < 0.01 (SYP); F_(3,41) = 6.047, P < 0.01 (IL-6); F_(3,31) = 5.974, P < 0.01 (FNDC5).

	5×FADCTL	5×FADProAHN	5×FAD+AHN(RUN)	5×FADΨAHN(RUN)
BDNF	100.00 ± 5.72 (8)	91.32 ± 3.80 (10)	149.74 ± 10.65** (8)	145.29 ± 13.09** (9)
PSD95	100.00 ± 7.07 (10)	103.19 ± 5.64 (15)	129.39 ± 6.47* (12)	128.23 ± 4.41* (8)
SYP	100.00 ± 6.02 (10)	102.03 ± 4.21 (15)	125.59 ± 7.04* (12)	125.02 ± 4.39* (8)
IL-6	100.00 ± 2.58 (10)	105.44 ± 3.86 (15)	128.89 ± 9.80* (12)	129.52 ± 6.74* (8)
FNDC5	100.00 ± 6.54 (8)	100.16 ± 7.49 (10)	131.78 ± 6.26* (8)	127.41 ± 7.03* (9)

^*P < 0.05;

^**P < 0.01 compared to 5×FAD^CTL and 5×FAD^ProAHN mice.