Fig. 3.

Time course of restenotic tissue characteristics on optical frequency-domain imaging (OFDI). Upper panels show OFDI images 7 months later. OFDI images of segment “A” 11 months later (middle panel) showed abundant bright puncta with backward attenuation. Bright puncta developed in the proximal stent segment without paclitaxel-coated balloon (PCB) dilatation, not in the distal stent segment with PCB dilatation. These were not observed on the intravascular ultrasound. On OFDI 16 months later (lower panels), heterogeneous tissue with bright puncta had progressed around the proximal stent edge.

*The restenotic lesion including segment “A” was dilated with a 3.0 mm scoring balloon 11 months later.