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. 2017 Dec 9;22(12):2187. doi: 10.3390/molecules22122187

Table 1.

Percent inhibition of compounds 3a3j, moclobemide and selegiline against MAO-A and MAO-B at 10−3 M to 10−4 M concentrations.

Comp. MAO A Inhibition % MAO B Inhibition %
10−3 M 10−4 M 10−3 M 10−4 M
3a 25.00 19.02 60.37 52.15
3b 30.08 20.45 30.46 26.88
3c 14.10 10.75 25.75 18.20
3d 18.88 12.71 23.97 17.75
3e 22.12 18.55 87.28 83.50
3f 30.77 18.30 75.66 68.30
3g 16.69 11.07 18.20 11.23
3h 25.89 21.30 82.58 79.10
3i 19.88 10.55 32.02 28.75
3j 22.15 17.28 34.60 30.50
Moclobemide 91.42 ± 4.60 77.86 ± 3.71 - -
Selegiline - - 97.69 ± 4.16 94.42 ± 3.89