Table 1.

Anti-proliferative effect of trihydroxyflavones. White color—EC₅₀ >50 µM, light grey—EC₅₀ <50 µM, dark grey—EC₅₀ <25 µM.

Compound	EC50 (µM)
	A549	MCF-7	U87
1	19.6 ± 4.5	21.6 ± 3.6	15.5 ± 5.4
2	>100.0	>100.0	>100.0
3	36.3 ± 4.6	12.6 ± 2.6	14.2 ± 4.8
4	>100.0	>100.0	>100.0
5	19.8 ± 8.3	36.0 ± 0.3	72.6 ± 4.6
6	75.3 ± 5.7	69.3 ± 3.5	80.4 ± 6.8
7	6.8 ± 0.6	11.2 ± 1.1	30.8 ± 2.8
8	>100.0	30.0 ± 0.6	59.8 ± 8.7
9	22.1 ± 2.0	16.2 ± 4.2	>100.0
10	37.6 ± 2.7	19.0 ± 5.7	59.5 ± 3.8
11	69.2 ± 0.6	23.1 ± 5.5	88.4 ± 14.4
12	>100.0	>100.0	>100.0
13	>100.0	15.9 ± 4.3	>100.0
14	>100.0	>100.0	>100.0
15	>100.0	71.5 ± 13.6	73.8 ± 13.6
API	77.5 ± 9.2	71.5 ± 15.6	>100.0
BCL	68.2 ± 3.6	26.1 ± 7.1	>100.0