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. 2018 Sep 17;10:3569–3577. doi: 10.2147/CMAR.S171855

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© 2018 Mao et al. This work is published and licensed by Dove Medical Press Limited

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(A) The distribution of tumor purity in three datasets. (B) The distribution of tumor purity among TNM stages, MMR status, and primary locations in microarray dataset. (C) The distribution of tumor purity among TNM stages, MMR status, and primary locations in TCGA dataset. (D) Kaplan–Meier analysis of overall survival showed low purity colon cancer (separated by X-tile) that conferred worse prognosis in microarray dataset.

Notes: ***P<0.001, **P=0.008.

Abbreviations: TNM, tumor node metastasis; MMR, DNA mismatch repair; dMMR, MMR-deficient; pMMR, MMR-proficient.