Figure 2.
Anxiolytic effects of diazepam (DZP, 1 mg/kg), 4-hydroxycinnamic acid (4-OH CA), and 4-chlorocinnamic acid (4-Cl CA) after intragastric administration in (A,B) mice and (C,D) rats. Elevated plus-maze (EPM) results are expressed by (A,C) the time spent in open arms and (B,D) the number of open-arm entries. Data are expressed as means ± SEM. * p < 0.05, ** p < 0.01, *** p < 0.001 vs. vehicle control, by Dunnett’s t-test.