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Comparison of morphology between 2D culture dish and 3D alginate architecture. (A). ∼ (C) Morphological changes onto 2D culture dish. Cuboidal hepatic morphology is forfeited as time goes on until day 7. (D)∼(F) Morphological changes compared between 2D. Cuboidal hepatic morphology is sustained until day 7 in 3D alginate architecture. (G) Magnification of (F). Black arrows indicate areas mimicking hepatic structure in 3D architectures. Bars, 100 μm.
