Table 3.
Baseline virological and histological features of HCV sustained virological responders (SVR) against non-responders (NR).
Virological and histological features | SVR (n = 86) |
NR (n = 74) |
χ2 |
P |
||
---|---|---|---|---|---|---|
Size (n) | Frequency (%) | Size (n) | Frequency (%) | |||
HCV-RNA Level, before therapy | ||||||
Low viral load | 43 | 50.0 | 27 | 36.5 | 3.1 | NS |
Moderate viral load | 39 | 45.3 | 37 | 50.0 | 0.2 | NS |
High viral load | 4 | 4.7 | 10 | 13.5 | 3.6 | NS |
HCV-RNA Level, after therapy | ||||||
Low viral load | 0 | 0 | 30 | 40.5 | 48.3 | S* |
Moderate viral load | 0 | 0 | 38 | 51.4 | 66.6 | S* |
High viral load | 0 | 0 | 6 | 8.1 | 6.3 | S |
Metavir Scoring System, before therapy | ||||||
Activity Score | ||||||
A0/1 | 72 | 83.7 | 52 | 70.3 | 4.3 | S |
A2/3 | 14 | 16.3 | 22 | 29.7 | 4.3 | S |
Fibrosis Score | ||||||
F0/1 | 54 | 62.8 | 18 | 24.3 | 28.6 | S* |
F2 | 20 | 23.3 | 30 | 40.5 | 6.04 | S |
F3/4 | 12 | 13.9 | 26 | 35.2 | 11.1 | S |
Metavir Scoring System, after therapy | ||||||
Activity Score | ||||||
A0/1 | 76 | 88.4 | 44 | 59.5 | 20.2 | S* |
A2/3 | 10 | 11.6 | 30 | 40.5 | 20.2 | S* |
Fibrosis Score | ||||||
F0/1 | 56 | 65.1 | 30 | 40.5 | 11.1 | S |
F2 | 24 | 27.9 | 12 | 16.2 | 3.3 | NS |
F3/4 | 6 | 7 | 32 | 43.3 | 33.0 | S* |
n: size of samples.
NS: represents no significant difference.
S: represents significant difference with Chi-square value (χ2 > 3.84).
S*: high significant difference with Chi-square value (χ2 > 3.84).