Table 6.
Correlation between hormonal profile and genotypes of P53 and CD95 at +72 G/C and −670 A/G polymorphic points.
| Hormonal profile (mean ± SE) | Gene | Genotypes | SVR (n = 86) | NR (n = 74) | P |
|---|---|---|---|---|---|
| Prolactin, (ng/mL) | P53 | 72 G/G | 12.91 ± 0.69 | 11.29 ± 0.71 | >0.05 |
| 72 G/C | 16.80 ± 0.99 | 16.25 ± 0.87 | >0.05 | ||
| 72 C/C | 9.32 ± 0.28 | 12.39 ± 0.20 | <0.01 | ||
| CD95 | −670 A/A | 10.24 ± 0.51 | 13.73 ± 0.55 | <0.01 | |
| −670 A/G | 14.02 ± 0.79 | 13.12 ± 0.57 | >0.05 | ||
| −670 G/G | 14.77 ± 0.65 | 13.09 ± 0.65 | >0.05 | ||
| Total Testosterone, (ng/mL) | P53 | 72 G/G | 1.74 ± 0.21 | 1.83 ± 0.36 | >0.05 |
| 72 G/C | 1.87 ± 0.22 | 2.09 ± 0.26 | >0.05 | ||
| 72 C/C | 2.84 ± 0.23 | 1.55 ± 0.22 | <0.01 | ||
| CD95 | −670 A/A | 2.09 ± 0.19 | 1.75 ± 0.30 | >0.05 | |
| −670 A/G | 2.26 ± 0.22 | 2.01 ± 0.28 | >0.05 | ||
| −670 G/G | 2.12 ± 0.25 | 1.80 ± 0.26 | >0.05 | ||
| GH, (ng/ml) | P53 | 72 G/G | 0.98 ± 0.02 | 0.41 ± 0.13 | <0.01 |
| 72 G/C | 0.75 ± 0.10 | 0.66 ± 0.36 | >0.05 | ||
| 72 C/C | 0.82 ± 0.12 | 0.83 ± 0.16 | >0.05 | ||
| CD95 | −670 A/A | 0.84 ± 0.06 | 0.56 ± 0.12 | <0.05 | |
| −670 A/G | 0.85 ± 0.08 | 0.57 ± 0.33 | >0.05 | ||
| −670 G/G | 0.86 ± 0.11 | 0.76 ± 0.20 | >0.05 |
S.E.: standard error.
n: size of samples.
<0.01: represents high significant difference (P < 0.01).
<0.05: represents significant difference (P < 0.05).
>0.05: represents no significant difference (P > 0.05).