Scheme 2.
Synthesis of target compounds. Conditions: (i) S, Et2NH, EtOH, NCCH2COOEt; (ii) R1CN, HCl, dioxane, EtOH; (iii) Ac2O, CH(OEt)3; (iv) NH2NH2·H2O; and (v) R2CHO, EtOH, AcOH.
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