Figure 13.

Microscopic images of bone tissue three months after the implantation of the experimental PLGA/PHB + IGF1 and control PLGA/PHB. M-material, CT-connective tissue, B-bone tissue, BM-bone marrow, GC-giant cell. PLGA/PHB + IGF1—left image: the material and connective tissue in the centre of the implant is visible; right image: trabeculae in the edge of the implant. PLGA/PHB—left image: the centre of the implant with visible fibrous structure; right image: the filament of material surrounded by the connective tissue and giant cells