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. 2017 Oct 28;22(11):1852. doi: 10.3390/molecules22111852

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Microscopic images of bone tissue six months after the implantation of the experimental PLGA/PHB + IGF1 and control PLGA/PHB. M-material, CT-connective tissue, B-bone tissue, BM-bone marrow, GC-giant cell. PLGA/PHB + IGF1—left image: the residues of material in bone marrow are visible; right image: the remains of the fibres surrounded by connective tissue are visible. PLGA/PHB—left image: the residues of material in the bone marrow; right image: loose and fibrous connective tissue around the material in the centre of implant is visible.