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. 2018 Jul 24;193(3):313–326. doi: 10.1111/cei.13150

Figure 8.

Figure 8

Compilation of percentages of Toll‐like receptor (TLR)2 responses above the interquartile range (IQR)‐based threshold of control responses. Compilation of percentages of control and multiple sclerosis (MS) patients with enhanced TLR2 responses as assessed in peripheral blood mononuclear cells (PBMC), CD14+ whole population and CD14+ single‐cell analyses. These studies encompass 26 MS patients (Table 1) and 32 healthy controls (Table 2). The percentages of progressive MS patients (Prog MS) with enhanced responses (mean = 60·13%) were significantly greater than those of the control patients (mean = 6·87%); P = 0.0098 via Kruskal–Wallis followed by Dunn's multiple comparisons test. The percentages of total MS patients (51·55%) and relapsing–remitting MS (RRMS) patients (41·65%) with enhanced responses were greater than those of the control patients, but did not reach statistical significance. Medians are depicted.